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The OhrR repressor senses organic hydroperoxides by reversible formation of a cysteine-sulfenic acid derivative

Reactive oxygen species induce the expression of detoxification and repair genes critical for life in an aerobic environment. Bacterial factors that sense reactive oxygen species use either thiol-disulfide exchange reactions (OxyR, RsrA) or redox labile 2Fe–2S clusters (SoxR). We demonstrate that th...

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Autori principali: Fuangthong, Mayuree, Helmann, John D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC124464/
https://ncbi.nlm.nih.gov/pubmed/11983871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102483199
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