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The c-Myc target gene PRDX3 is required for mitochondrial homeostasis and neoplastic transformation

Deregulated expression of the c-Myc transcription factor is found in a wide variety of human tumors. Because of this significant role in oncogenesis, considerable effort has been devoted to elucidating the molecular program initiated by deregulated c-myc expression. The primary transforming activity...

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Bibliographic Details
Main Authors: Wonsey, Diane R., Zeller, Karen I., Dang, Chi V.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124457/
https://ncbi.nlm.nih.gov/pubmed/12011429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102523299
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