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Inhibition of mitochondrial protein synthesis results in increased endothelial cell susceptibility to nitric oxide-induced apoptosis

Mutations in mitochondrial DNA, affecting the activity of respiratory complexes, have been implicated in many chronic degenerative diseases. Mitochondrial proteins coded for by both the mitochondrial and nuclear genes are known to have important signaling roles in apoptosis. However, the impact of t...

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Bibliographic Details
Main Authors: Ramachandran, Anup, Moellering, Douglas R., Ceaser, Erin, Shiva, Sruti, Xu, Jun, Darley-Usmar, Victor
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124456/
https://ncbi.nlm.nih.gov/pubmed/12011428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102019899
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