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Diagnosis of multiple cancer types by shrunken centroids of gene expression

We have devised an approach to cancer class prediction from gene expression profiling, based on an enhancement of the simple nearest prototype (centroid) classifier. We shrink the prototypes and hence obtain a classifier that is often more accurate than competing methods. Our method of “nearest shru...

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Detalhes bibliográficos
Main Authors: Tibshirani, Robert, Hastie, Trevor, Narasimhan, Balasubramanian, Chu, Gilbert
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124443/
https://ncbi.nlm.nih.gov/pubmed/12011421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082099299
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