Urokinase–urokinase receptor interaction mediates an inhibitory signal for HIV-1 replication

Elevated levels of soluble urokinase-type plasminogen activator (uPA) receptor, CD87/u-PAR, predict survival in individuals infected with HIV-1. Here, we report that pro-uPA (or uPA) inhibits HIV-1 expression in U937-derived chronically infected promonocytic U1 cells stimulated with phorbol 12-myris...

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Detalles Bibliográficos
Main Authors: Alfano, Massimo, Sidenius, Nicolai, Panzeri, Barbara, Blasi, Francesco, Poli, Guido
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC124389/
https://ncbi.nlm.nih.gov/pubmed/12084931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.142078099
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