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CD25+CD4+ T cells contribute to the control of memory CD8+ T cells

Previously we demonstrated that IL-15 and IL-2 control the number of memory CD8+ T cells in mice. IL-15 induces, and IL-2 suppresses the division of these cells. Here we show that CD25+CD4+ regulatory T cells play an important role in the IL-2-mediated control of memory phenotype CD8+ T cell number....

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Main Authors: Murakami, Masaaki, Sakamoto, Akemi, Bender, Jeremy, Kappler, John, Marrack, Philippa
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC124384/
https://ncbi.nlm.nih.gov/pubmed/12084927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132254399
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