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A cytosine methyltransferase homologue is essential for repeat-induced point mutation in Neurospora crassa

During sexual development, Neurospora crassa inactivates genes in duplicated DNA segments by a hypermutation process, repeat-induced point mutation (RIP). RIP introduces C:G to T:A transition mutations and creates targets for subsequent DNA methylation in vegetative tissue. The mechanism of RIP and...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Freitag, Michael, Williams, Rebecca L., Kothe, Gregory O., Selker, Eric U.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124379/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072568/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.132212899
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