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Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis

During spermiogenesis (the maturation of spermatids into spermatozoa) in many vertebrate species, protamines replace histones to become the primary DNA-packaging protein.It has long been thought that this process is facilitated by the hyperacetylation of histone H4. However, the responsible histone...

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Autores principales: Lahn, Bruce T., Tang, Zhao Lan, Zhou, Jianxin, Barndt, Robert J., Parvinen, Martti, Allis, C. David, Page, David C.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC124363/
https://ncbi.nlm.nih.gov/pubmed/12072557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082248899
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