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Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis

During spermiogenesis (the maturation of spermatids into spermatozoa) in many vertebrate species, protamines replace histones to become the primary DNA-packaging protein.It has long been thought that this process is facilitated by the hyperacetylation of histone H4. However, the responsible histone...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lahn, Bruce T., Tang, Zhao Lan, Zhou, Jianxin, Barndt, Robert J., Parvinen, Martti, Allis, C. David, Page, David C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124363/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072557/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.082248899
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