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An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells

It has been believed that XIST RNA requires a discrete window in early development to initiate the series of chromatin-remodeling events that form the heterochromatic inactive X chromosome. Here we investigate four adult male HT-1080 fibrosarcoma cell lines expressing ectopic human XIST and demonstr...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Hall, Lisa L., Byron, Meg, Sakai, Kosuke, Carrel, Laura, Willard, Huntington F., Lawrence, Jeanne B.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124357/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.132468999
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