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Using deeply trapped intermediates to map the cytochrome c folding landscape
Replacement of iron with cobalt(III) selectively introduces a deep trap in the folding-energy landscape of the heme protein cytochrome c. Remarkably, neither the protein structure nor the folding thermodynamics is perturbed by this metal–ion substitution, as shown by data from spectroscopic and x-ra...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124336/ https://ncbi.nlm.nih.gov/pubmed/12084923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132254499 |
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