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Permissive proteolytic activity for visual cortical plasticity

The serine protease, tissue-type plasminogen activator (tPA) is a key regulator of extracellular proteolytic cascades. We demonstrate a requirement for tPA signaling in the experience-dependent plasticity of mouse visual cortex during the developmental critical period. Proteolytic activity by tPA in...

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Detalhes bibliográficos
Main Authors: Mataga, Nobuko, Nagai, Nobuo, Hensch, Takao K.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124331/
https://ncbi.nlm.nih.gov/pubmed/12032349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.102088899
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