Insight into the molecular basis of pathogen abundance: Group A Streptococcus inhibitor of complement inhibits bacterial adherence and internalization into human cells

Streptococcal inhibitor of complement (Sic) is a secreted protein made predominantly by serotype M1 Group A Streptococcus (GAS), which contributes to persistence in the mammalian upper respiratory tract and epidemics of human disease. Unexpectedly, an isogenic sic-negative mutant adhered to human ep...

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Detalhes bibliográficos
Principais autores: Hoe, Nancy P., Ireland, Robin M., DeLeo, Frank R., Gowen, Brian B., Dorward, David W., Voyich, Jovanka M., Liu, Mengyao, Burns, Eugene H., Culnan, Derek M., Bretscher, Anthony, Musser, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124310/
https://ncbi.nlm.nih.gov/pubmed/12032337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112039899
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