Macrophage elimination increases bacterial translocation and gut-origin septicemia but attenuates symptoms and mortality rate in a model of systemic inflammation.

OBJECTIVE: The central question tested in this study was whether dichloromethylene-diphosphonate (CL2MDP) liposome-mediated elimination of hepatic and splenic macrophages would influence zymosan-induced bacterial translocation and the zymosan-induced generalized inflammatory response. SUMMARY BACKGR...

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Detalhes bibliográficos
Main Authors: Nieuwenhuijzen, G A, Haskel, Y, Lu, Q, Berg, R D, van Rooijen, N, Goris, R J, Deitch, E A
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1243076/
https://ncbi.nlm.nih.gov/pubmed/8257230
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