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ERK2 enters the nucleus by a carrier-independent mechanism

In stimulated cells, the mitogen-activated protein kinase ERK2 (extracellular signal-regulated kinase 2) concentrates in the nucleus. Evidence exists for CRM1-dependent, mitogen-activated protein kinase kinase-mediated nuclear export of ERK2, but its mechanism of nuclear entry is not understood. To...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Whitehurst, Angelique W., Wilsbacher, Julie L., You, Youngjai, Luby-Phelps, Kate, Moore, Mary Shannon, Cobb, Melanie H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124259/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12032311/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.112495999
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