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Mutation of the Drosophila homologue of the Myb protooncogene causes genomic instability

Vertebrates have three related Myb genes. The c-Myb protooncogene is required for definitive hematopoiesis in mice and when mutated causes leukemias and lymphomas in birds and mammals. The A-Myb gene is required for spermatogenesis and mammary gland proliferation in mice. The ubiquitously expressed...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Manak, J. Robert, Mitiku, Nesanet, Lipsick, Joseph S.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124249/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12032301/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.122231599
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