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The crystal structure of the C-terminal fragment of striated-muscle α-tropomyosin reveals a key troponin T recognition site

Contraction in striated and cardiac muscles is regulated by the motions of a Ca(2+)-sensitive tropomyosin/troponin switch. In contrast, troponin is absent in other muscle types and in nonmuscle cells, and actomyosin regulation is myosin-linked. Here we report an unusual crystal structure at 2.7 Å of...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Li, Yu, Mui, Suet, Brown, Jerry H., Strand, James, Reshetnikova, Ludmilla, Tobacman, Larry S., Cohen, Carolyn
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124239/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12032291/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.102179999
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