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Spatial regulation of the cAMP-dependent protein kinase during chemotactic cell migration

Historically, the cAMP-dependent protein kinase (PKA) has a paradoxical role in cell motility, having been shown to both facilitate and inhibit actin cytoskeletal dynamics and cell migration. In an effort to understand this dichotomy, we show here that PKA is regulated in subcellular space during ce...

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Detalhes bibliográficos
Main Authors: Howe, Alan K., Baldor, Linda C., Hogan, Brian P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242330/
https://ncbi.nlm.nih.gov/pubmed/16176981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507072102
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