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Partner-regulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages
IFN regulatory factor (IRF) 8 is a transcription factor that directs macrophage differentiation. By fluorescence recovery after photobleaching, we visualized the movement of IRF8-GFP in differentiating macrophages. Recovery data fitted to mathematical models revealed two binding states for IRF8. The...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1242294/ https://ncbi.nlm.nih.gov/pubmed/16183743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504014102 |
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