Relationship between the expression of cyclooxygenase 2 and MDR1/P-glycoprotein in invasive breast cancers and their prognostic significance

INTRODUCTION: Recent reports suggest that expression of the cyclooxygenase 2 (COX-2) enzyme may up-regulate expression of MDR1/P-glycoprotein (MDR1/P-gp), an exponent of resistance to cytostatic drugs. The present study aimed at examining the relationship between the expression of COX-2 and of MDR1/...

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Main Authors: Surowiak, Pawel, Materna, Verena, Matkowski, Rafal, Szczuraszek, Katarzyna, Kornafel, Jan, Wojnar, Andrzej, Pudelko, Marek, Dietel, Manfred, Denkert, Carsten, Zabel, Maciej, Lage, Hermann
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242165/
https://ncbi.nlm.nih.gov/pubmed/16168133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1313
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