HSV-mediated gene transfer of vascular endothelial growth factor to dorsal root ganglia prevents diabetic neuropathy

We examined the utility of herpes simplex virus (HSV) vector-mediated gene transfer of vascular endothelial growth factor (VEGF) in a mouse model of diabetic neuropathy. A replication-incompetent HSV vector with VEGF under the control of the HSV ICP0 promoter (vector T0VEGF) was constructed. T0VEGF...

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Bibliographic Details
Main Authors: Chattopadhyay, M, Krisky, D, Wolfe, D, Glorioso, JC, Mata, M, Fink, DJ
Format: Artigo
Language:Inglês
Published: 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1242112/
https://ncbi.nlm.nih.gov/pubmed/15843809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3302533
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