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Reductions in blood lead overestimate reductions in brain lead following repeated succimer regimens in a rodent model of childhood lead exposure.

Although many studies have demonstrated the efficacy of succimer chelation in reducing blood and brain lead levels, the relative efficacy of the drug in the two tissues is less well understood. This issue is important because blood lead levels after chelation are used clinically to estimate reductio...

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Autores principales: Stangle, Diane E, Strawderman, Myla S, Smith, Donald, Kuypers, Mareike, Strupp, Barbara J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1241858/
https://ncbi.nlm.nih.gov/pubmed/14998744
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