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Cysteine-modifying agents: a possible approach for effective anticancer and antiviral drugs.

Modification of cysteine residues in proteins, due to a) the participation of the thiol moiety of this amino acid in oxido-reduction reactions, b) its ability to strongly coordinate transition metal ions, or c) its nucleophilic nature and facile reaction with electrophiles, may be critically importa...

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Autors principals: Casini, Angela, Scozzafava, Andrea, Supuran, Claudiu T
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1241249/
https://ncbi.nlm.nih.gov/pubmed/12426135
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