Irreversible binding and adrenocorticolytic activity of the DDT metabolite 3-methylsulfonyl-DDE examined in tissue-slice culture.

The persistent adrenocorticolytic DDT metabolite 3-methylsulfonyl-DDE (MeSO(2)-DDE) was originally identified in Baltic grey seals, a population suffering from adrenocortical hyperplasia. In mice, MeSO(2)-DDE induces mitochondrial degeneration and cellular necrosis in the adrenal zona fasciculata. I...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lindhe , O, Lund, B O, Bergman , A, Brandt, I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Institute of Environmental Health Science 2001
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1240628/
https://ncbi.nlm.nih.gov/pubmed/11266318
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