Formamidopyrimidine-DNA glycosylase enhances arsenic-induced DNA strand breaks in PHA-stimulated and unstimulated human lymphocytes.

To confirm that arsenic (As) induces oxidative DNA damage in phytohemagglutinin (PHA)-stimulated and unstimulated human lymphocytes, we used the alkaline comet assay combined with specific enzyme [formamidopyrimidine-DNA glycosylase (FPG)] digestion to measure As-induced base damage. The results sho...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, D, Morimoto, K, Takeshita, T, Lu, Y
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2001
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1240313/
https://ncbi.nlm.nih.gov/pubmed/11401765
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