Uric Acid Is a Genuine Metabolite of Penicillium cyclopium and Stimulates the Expression of Alkaloid Biosynthesis in This Fungus

On searching for endogenous, low-molecular-weight effectors of benzodiazepine alkaloid biosynthesis in Penicillium cyclopium uric acid was isolated from ethanolic or autoclaved mycelial extracts of this fungus. The isolation was based on a three-step high-pressure liquid chromatography procedure gui...

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Bibliographic Details
Main Authors: Helbig, Florian, Steighardt, Jörg, Roos, Werner
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Mycology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC123850/
https://ncbi.nlm.nih.gov/pubmed/11916664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.4.1524-1533.2002
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