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Engineering of a Bacillus subtilis Strain with Adjustable Levels of Intracellular Biotin for Secretory Production of Functional Streptavidin

Streptavidin is a biotin-binding protein which has been widely used in many in vitro and in vivo applications. Because of the ease of protein recovery and availability of protease-deficient strains, the Bacillus subtilis expression-secretion system is an attractive system for streptavidin production...

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Bibliographic Details
Main Authors: Wu, Sau-Ching, Wong, Sui-Lam
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC123784/
https://ncbi.nlm.nih.gov/pubmed/11872456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.3.1102-1108.2002
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