Mechanism of IFN-γ-induced Endocytosis of Tight Junction Proteins: Myosin II-dependent Vacuolarization of the Apical Plasma Membrane

Disruption of epithelial barrier by proinflammatory cytokines such as IFN-γ represents a major pathophysiological consequence of intestinal inflammation. We have previously shown that IFN-γ increases paracellular permeability in model T84 epithelial cells by inducing endocytosis of tight junction (T...

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Bibliografiske detaljer
Main Authors: Utech, Markus, Ivanov, Andrei I., Samarin, Stanislav N., Bruewer, Matthias, Turner, Jerrold R., Mrsny, Randall J., Parkos, Charles A., Nusrat, Asma
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2005
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237102/
https://ncbi.nlm.nih.gov/pubmed/16055505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-03-0193
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