Helicobacter pylori VacA Cytotoxin: A Probe for a Clathrin-independent and Cdc42-dependent Pinocytic Pathway Routed to Late Endosomes

The vacuolating cytotoxin VacA is a major virulence factor of Helicobacter pylori, a bacterium responsible for gastroduodenal ulcers and cancer. VacA associates with lipid rafts, is endocytosed, and reaches the late endocytic compartment where it induces vacuolation. We have investigated the endocyt...

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Bibliographic Details
Main Authors: Gauthier, Nils C., Monzo, Pascale, Kaddai, Vincent, Doye, Anne, Ricci, Vittorio, Boquet, Patrice
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2005
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237088/
https://ncbi.nlm.nih.gov/pubmed/16055501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-05-0398
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