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BMP Regulation of Early Osteoblast Genes in Human Marrow Stromal Cells is Mediated by ERK and PI3-K Signaling

Bone marrow stromal cells (MSC) are the major source of osteoblasts for bone remodeling and repair in postnatal animals. Rodent MSC cultured with bone morphogenetic proteins (BMPs) differentiate into osteoblasts, but most human MSC show a poor osteogenic response to BMPs. Here we demonstrate that BM...

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Autores principales: Osyczka, Anna M, Leboy, Phoebe S
Formato: Artigo
Lenguaje:Inglês
Publicado: 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237031/
https://ncbi.nlm.nih.gov/pubmed/15905316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2005-0303
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