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Manganese Superoxide Dismutase Protects against Oxidation-Induced Apoptosis in Mouse Retinal Pigment Epithelium: Implications for Age-Related Macular Degeneration

PURPOSE: Oxidative stress from reactive oxygen species (ROS) has been implicated in many diseases, including age-related macular degeneration (AMD), in which the retinal pigment epithelium (RPE) is considered a primary target. Because manganese superoxide dismutase (SOD2), localized in mitochondria,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kasahara, Emiko, Lin, Li-Ren, Ho, Ye-Shih, Reddy, Venkat N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1237007/
https://ncbi.nlm.nih.gov/pubmed/16123448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-0344
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