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Role of poly(ADP-ribosyl)ation in DNA-PK(cs)- independent V(D)J recombination
V(D)J recombination is critical to the generation of a functional immune system. Intrinsic to the assembly of antigen receptor genes is the formation of endogenous DNA double-strand breaks, which normally are excluded from the cellular surveillance machinery because of their sequestration in a synap...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123682/ https://ncbi.nlm.nih.gov/pubmed/11930007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072495299 |
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