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Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development

The Mitf-Tfe family of basic helix–loop–helix-leucine zipper (bHLH-Zip) transcription factors encodes four family members: Mitf, Tfe3, Tfeb, and Tfec. In vitro, each protein in the family can bind DNA as a homo- or heterodimer with other family members. Mutational studies in mice have shown that Mit...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Steingrímsson, Eiríkur, Tessarollo, Lino, Pathak, Bhavani, Hou, Ling, Arnheiter, Heinz, Copeland, Neal G., Jenkins, Nancy A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC123673/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11930005/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.072071099
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