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Identification of a protein essential for a major pathway used by human cells to avoid UV- induced DNA damage
When DNA replication stalls at a fork-blocking lesion, cells use damage tolerance pathways to continue replication. One pathway, “translesion synthesis,” involves specialized DNA polymerases that can use damaged DNA as a template. Translesion synthesis can result in mutations (i.e., can be error-pro...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC123670/ https://ncbi.nlm.nih.gov/pubmed/11917106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062047799 |
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