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Pharmacological manipulation of Bcl-2 family members to control cell death

The commitment to programmed cell death involves complex interactions among pro- and antiapoptotic members of the Bcl-2 family of proteins. The physiological result of a decision by these proteins to undergo cell death is permeabilization of the mitochondrial outer membrane. Pharmacologic manipulati...

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Detalhes bibliográficos
Autor principal: Letai, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236690/
https://ncbi.nlm.nih.gov/pubmed/16200198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26250
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