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Shifting gears: liver SR-BI drives reverse cholesterol transport in macrophages

Cholesterol efflux from macrophages, the first step in reverse cholesterol transport (RCT), is assumed to play a critical role in the pathogenesis of atherosclerosis. However, in vivo proof supporting this hypothesis is lacking, due to difficulties in determining the activity of this first step in R...

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Detalhes bibliográficos
Main Authors: van der Velde, Astrid E., Groen, Albert K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236689/
https://ncbi.nlm.nih.gov/pubmed/16200207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26241
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