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A nuclear degradation pathway controls the abundance of normal mRNAs in Saccharomyces cerevisiae

We previously demonstrated an increased degradation of mRNAs in mutants of Saccharomyces cerevisiae having blocks in nuclear export. The degradation activity, designated DRN (degradation of mRNA in the nucleus), requires Cbc1p, a nuclear cap-binding protein, and Rrp6p, a nuclear exosome component. M...

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書誌詳細
主要な著者: Kuai, Letian, Das, Biswadip, Sherman, Fred
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236574/
https://ncbi.nlm.nih.gov/pubmed/16166263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506518102
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