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Collagen triple-helix formation in all-trans chains proceeds by a nucleation/growth mechanism with a purely entropic barrier

Collagen consists of repetitive Gly–Xaa–Yaa tripeptide units with proline and hydroxyproline frequently found in the Xaa and Yaa position, respectively. This sequence motif allows the formation of a highly regular triple helix that is stabilized by steric (entropic) restrictions in the constituent p...

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Bibliografiska uppgifter
Huvudupphovsmän: Bachmann, Annett, Kiefhaber, Thomas, Boudko, Sergei, Engel, Jürgen, Bächinger, Hans Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236557/
https://ncbi.nlm.nih.gov/pubmed/16172389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505141102
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