Cooperative subunit interactions in C-type inactivation of K channels.

C-type inactivation of potassium channels is distinct from N-terminal mediated (N-type) inactivation and involves a closing of the outer mouth of the channel. We have investigated the role of the individual subunits of the tetrameric channel in the C-type inactivation conformational change by compar...

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Autori principali: Ogielska, E M, Zagotta, W N, Hoshi, T, Heinemann, S H, Haab, J, Aldrich, R W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236482/
https://ncbi.nlm.nih.gov/pubmed/8599651
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