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Structural and functional similarities between the nucleotide-binding domains of CFTR and GTP-binding proteins.

The opening and closing of the CFTR Cl- channel are regulated by ATP hydrolysis at its two nucleotide binding domains (NBDs). However, the mechanism and functional significance of ATP hydrolysis are unknown. Sequence similarity between the NBDs of CFTR and GTP-binding proteins suggested the NBDs mig...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Carson, M R, Welsh, M J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236481/
https://ncbi.nlm.nih.gov/pubmed/8599650
Etiketak: Etiketa erantsi
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