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Gramicidin A channels switch between stretch activation and stretch inactivation depending on bilayer thickness

The patch clamp-liposome technique was used to examine the stretch sensitivity of a model membrane ion channel, gramicidin A, in membrane patches of different bilayer thickness. We found that small changes in phospholipid acyl chain length (i.e., PC-20 to PC-18) can switch gramicidin A from a stretc...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Martinac, Boris, Hamill, Owen P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 2002
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC123644/
https://ncbi.nlm.nih.gov/pubmed/11904391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.072632899
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