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Diacylglycerol analogs inhibit the rod cGMP-gated channel by a phosphorylation-independent mechanism.

The electrical response to light in retinal rods is mediated by cyclic nucleotide-gated, nonselective cation channels in the outer segment plasma membrane. Although cGMP appears to be the primary light-regulated second messenger, cellular levels of other substances, including Ca2+ and phosphatidylin...

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Podrobná bibliografie
Hlavní autoři: Gordon, S. E., Downing-Park, J., Tam, B., Zimmerman, A. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1236265/
https://ncbi.nlm.nih.gov/pubmed/8527654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0006-3495(95)79913-1
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