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Using RNA interference to identify genes required for RNA interference

RNA interference (RNAi) is a phenomenon in which double-stranded RNA (dsRNA) silences endogenous gene expression. By injecting pools of dsRNAs into Caenorhabditis elegans, we identified a dsRNA that acts as a potent suppressor of the RNAi mechanism. We have used coinjection of dsRNAs to identify fou...

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Detalhes bibliográficos
Main Authors: Dudley, Nathaniel R., Labbé, Jean-Claude, Goldstein, Bob
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123624/
https://ncbi.nlm.nih.gov/pubmed/11904378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062605199
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