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Identification and Functional Evaluation of Cellular and Viral Factors Involved in the Alteration of Nuclear Architecture during Herpes Simplex Virus 1 Infection

Herpes simplex virus 1 (HSV-1) replicates in the nucleus of host cells and radically alters nuclear architecture as part of its replication process. Replication compartments (RCs) form, and host chromatin is marginalized. Chromatin is later dispersed, and RCs spread past it to reach the nuclear edge...

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Detalhes bibliográficos
Main Authors: Simpson-Holley, Martha, Colgrove, Robert C., Nalepa, Grzegorz, Harper, J. Wade, Knipe, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235858/
https://ncbi.nlm.nih.gov/pubmed/16188986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.20.12840-12851.2005
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