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Huntington Disease Phenocopy Is a Familial Prion Disease

Huntington disease (HD) is a common autosomal dominant neurodegenerative disease with early adult–onset motor abnormalities and dementia. Many studies of HD show that huntingtin (CAG)n repeat–expansion length is a sensitive and specific marker for HD. However, there are a significant number of examp...

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Detalhes bibliográficos
Main Authors: Moore, Richard C., Xiang, Fengqing, Monaghan, Jeffrey, Han, Dong, Zhang, Zhiping, Edström, Lars, Anvret, Maria, Prusiner, Stanley B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1235549/
https://ncbi.nlm.nih.gov/pubmed/11593450
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