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AT-Rich Palindromes Mediate the Constitutional t(11;22) Translocation

The constitutional t(11;22) translocation is the only known recurrent non-Robertsonian translocation in humans. Offspring are susceptible to der(22) syndrome, a severe congenital anomaly disorder caused by 3:1 meiotic nondisjunction events. We previously localized the t(11;22) translocation breakpoi...

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Main Authors: Edelmann, L., Spiteri, E., Koren, K., Pulijaal, V., Bialer, M. G., Shanske, A., Goldberg, R., Morrow, B. E.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society of Human Genetics 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234939/
https://ncbi.nlm.nih.gov/pubmed/11095996
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