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The 28-kb Deletion Spanning D15S63 Is a Polymorphic Variant in the Ashkenazi Jewish Population

D15S63 is one of the loci, on chromosome 15q11-q13, that exhibit parent-of-origin dependent methylation and that is commonly used in the diagnosis of Prader-Willi or Angelman syndromes (PWS/AS). A 28-kb deletion spanning the D15S63 locus was identified in five unrelated patients; in each of them the...

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Autors principals: Silverstein, Shira, Lerer, Israela, Buiting, Karin, Abeliovich, Dvorah
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Human Genetics 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234924/
https://ncbi.nlm.nih.gov/pubmed/11083946
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