Population Structure in Admixed Populations: Effect of Admixture Dynamics on the Pattern of Linkage Disequilibrium

Gene flow between genetically distinct populations creates linkage disequilibrium (admixture linkage disequilibrium [ALD]) among all loci (linked and unlinked) that have different allele frequencies in the founding populations. We have explored the distribution of ALD by using computer simulation of...

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Main Authors: Pfaff, C. L., Parra, E. J., Bonilla, C., Hiester, K., McKeigue, P. M., Kamboh, M. I., Hutchinson, R. G., Ferrell, R. E., Boerwinkle, E., Shriver, M. D.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2001
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234913/
https://ncbi.nlm.nih.gov/pubmed/11112661
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