Gene transfer to the thymus. A means of abrogating the immune response to recombinant adenovirus.

OBJECTIVE: The authors investigated whether adenoviral gene transfer to the thymus could be accomplished in vivo and whether immunologic unresponsiveness to recombinant adenovirus could be induced by intrathymic inoculation. SUMMARY BACKGROUND DATA: A major barrier to the clinical application of ade...

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Detalhes bibliográficos
Main Authors: DeMatteo, R P, Raper, S E, Ahn, M, Fisher, K J, Burke, C, Radu, A, Widera, G, Claytor, B R, Barker, C F, Markmann, J F
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234797/
https://ncbi.nlm.nih.gov/pubmed/7677454
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