Predictive DNA testing and prophylactic thyroidectomy in patients at risk for multiple endocrine neoplasia type 2A.

BACKGROUND: Missense germ-line mutations in the RET protooncogene are associated with multiple endocrine neoplasia type 2A (MEN 2A). Detection of these mutant alleles in kindred members predicts disease inheritance and provides the basis for preventative thyroidectomy. METHODS: A polymerase chain re...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wells, S A, Chi, D D, Toshima, K, Dehner, L P, Coffin, C M, Dowton, S B, Ivanovich, J L, DeBenedetti, M K, Dilley, W G, Moley, J F
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1234374/
https://ncbi.nlm.nih.gov/pubmed/7916559
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados